TRIM35

Across TCGA pan-cancer cohorts, TRIM35 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TRIM35 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher TRIM35 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRIM35 expression acts as an unfavorable survival marker.

LSCC are the cancer types where TRIM35 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.247	0.803	.022	2	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

TRIM35–LSCC (DFS)

Open the LSCC breakdown →