TRIM34

Across TCGA cell cohorts, TRIM34 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,220 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TRIM34-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Intracellular receptor signaling pathway, and Negative regulation of IP-10 production. Each is linked with TRIM34 in more than 14 cancer types. Because this analysis shows association rather than direction, both TRIM34-to-partner and partner-to-TRIM34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic pattern recognition receptor signaling pathway grouped by TRIM34-low versus TRIM34-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM34→partner) and Y-score (partner→TRIM34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cytoplasmic pattern recognition receptor signaling pathway →	+0.095	+2.260	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Intracellular receptor signaling pathway →	+0.077	+1.462	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of IP-10 production →	+1.383	+1.827	<.001	<.001	3	15
BONE	Positive regulation of protein localization to plasma membrane →	+0.112	+1.200	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of cytokine-mediated signaling pathway →	+0.098	+1.118	<.001	.001	3	13
STOMACH	Innate immune response-activating signaling pathway →	+0.084	+1.730	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,220 associations by consensus.

Cytoplasmic pattern recognition receptor signaling pathway by TRIM34 expression — STOMACH

Explore this box plot interactively →