Across TCGA patient cohorts, TRIM33 protein abundance is significantly associated with the RNA expression of many other genes, with 15,493 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM33-associated genes across cancer lineages are AUNIP, SASS6, and CDC25A. Each is linked with TRIM33 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRIM33-to-partner and partner-to-TRIM33 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM33→partner) and Y-score (partner→TRIM33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AUNIP →	+0.858	+0.279	<.001	<.001	3	8
LSCC	SASS6 →	+0.685	+0.205	<.001	<.001	3	8
OV	CDC25A →	+0.797	+0.224	<.001	.002	3	8
HNSC	SIKE1 →	+0.766	+0.289	<.001	<.001	3	8
LSCC	TTF2 →	+0.791	+0.330	<.001	<.001	3	8
HNSC	RBM15 →	+0.561	+0.208	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,493 associations by consensus.

Exploration

TRIM33 survival (RNA) · tumor vs normal (RNA) · all TRIM33 data types