Across TCGA patient cohorts, TRIM33 mutation is significantly associated with the RNA expression of many other genes, with 4,598 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM33-associated genes across cancer lineages are SKA1, CENPN, and PSAT1. Each is linked with TRIM33 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM33-to-partner and partner-to-TRIM33 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM33→partner) and Y-score (partner→TRIM33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKA1 →	+0.741	+2.233	<.001	<.001	3	3
UCEC	CENPN →	+0.775	+2.057	<.001	<.001	3	3
UCEC	PSAT1 →	+0.658	+1.263	.002	.002	3	3
CESC	FOXN3P1 →	+0.030	+2.870	.001	.006	3	2
CESC	RNA5SP72 →	+0.124	+3.984	<.001	.009	3	2
UCEC	CASC15 →	-0.336	-3.416	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,598 associations by consensus.

Exploration

TRIM33 survival (RNA) · tumor vs normal (RNA) · all TRIM33 data types