Across TCGA cell cohorts, TRIM33 mutation is significantly associated with the mutation status of many other genes, with 3,913 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIM33-associated genes across cancer lineages are MYH7B, NIN, and UBR4. Each is linked with TRIM33 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRIM33-to-partner and partner-to-TRIM33 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM33→partner) and Y-score (partner→TRIM33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYH7B →	+2.870	+3.347	.009	.009	1	6
PANCREAS	NIN →	+5.115	+5.115	.005	.005	1	5
STOMACH	UBR4 →	+2.192	+3.628	.009	.009	1	5
STOMACH	MYO9B →	+2.415	+3.807	.006	.006	1	5
BLOOD_Leukemia	PCDHGC3 →	+3.700	+4.498	<.001	<.001	1	5
LARGE_INTESTINE	JAK3 →	+3.886	+3.886	<.001	<.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,913 associations by consensus.

Exploration

TRIM33 survival (RNA) · tumor vs normal (RNA) · all TRIM33 data types