TRIM32

Across TCGA pan-cancer cohorts, TRIM32 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TRIM32 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TRIM32 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRIM32 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

CCRCC, COAD, and PDAC are the cancer types where TRIM32 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.502	1.000	.010	9	view →
COAD	DFS	Median	II,III,IV	1.000	0.937	.047	6	view →
PDAC	OS	Median	III,IV	0.253	0.572	.020	6	view →
LSCC	DFS	Quartile	All	0.708	0.906	.031	5	view →
HNSC	DFS	Quartile	IV	0.913	0.677	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TRIM32–CCRCC (DFS)

Open the CCRCC breakdown →