Across TCGA patient cohorts, TRIM31 mutation is significantly associated with the RNA expression of many other genes, with 1,795 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM31-associated genes across cancer lineages are NOL12, HIRIP3, and CHAF1A. Each is linked with TRIM31 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM31-to-partner and partner-to-TRIM31 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM31→partner) and Y-score (partner→TRIM31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NOL12 →	+0.382	+2.534	<.001	.001	3	2
UCEC	HIRIP3 →	+0.465	+2.732	.003	.003	3	2
UCEC	CHAF1A →	+0.718	+3.191	<.001	<.001	3	2
SKCM	NCAPH2 →	+0.744	+3.207	<.001	.009	3	2
UCEC	PLEKHH3 →	+0.461	+2.513	.007	.001	3	2
BLCA	MIR301B →	+0.261	+4.814	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,795 associations by consensus.

Exploration

TRIM31 survival (RNA) · tumor vs normal (RNA) · all TRIM31 data types