TRIM31-AS1

Across TCGA pan-cancer cohorts, TRIM31-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated TRIM31-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TRIM31-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRIM31-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and READ show a favorable association.

ACC, COAD, and READ are the cancer types where TRIM31-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.867	0.382	<.001	149	view →
COAD	DFS	Tertile	All	0.542	0.782	<.001	45	view →
READ	DFS	Tertile	All	0.910	0.209	<.001	37	view →
KIRC	DFS	Quartile	III,IV	0.876	0.707	.006	25	view →
PRAD	DFS	Median	All	0.870	0.698	.003	18	view →
CHOL	DFS	Tertile	All	0.736	0.150	.007	15	view →
OV	DFS	Tertile	IV	0.354	0.618	.009	12	view →
MESO	OS	Median	II,III,IV	0.618	0.493	.027	12	view →
LGG	DFS	Quartile	All	0.898	0.811	.008	10	view →
UVM	DFS	Tertile	III,IV	0.200	0.703	.044	9	view →
THCA	OS	Median	IV	0.570	0.924	.012	9	view →
ESCA	OS	Median	All	0.617	1.000	.009	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

TRIM31-AS1–ACC (OS)

Open the ACC breakdown →