TRIM3

Across TCGA cell cohorts, TRIM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,275 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TRIM3-associated GO terms across cancer lineages are Regulation of cilium assembly, Protein K63-linked ubiquitination, and Negative regulation of organelle assembly. Each is linked with TRIM3 in more than 16 cancer types. Because this analysis shows association rather than direction, both TRIM3-to-partner and partner-to-TRIM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cilium assembly grouped by TRIM3-low versus TRIM3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM3→partner) and Y-score (partner→TRIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of cilium assembly →	+0.069	+1.138	<.001	<.001	3	17
KIDNEY	Protein K63-linked ubiquitination →	+0.073	+0.690	<.001	<.001	3	15
BONE	Negative regulation of organelle assembly →	+0.070	+0.862	.001	.004	3	14
URINARY_TRACT	Telomere tethering at nuclear periphery →	+0.143	+1.356	.007	.001	3	14
OESOPHAGUS	Cytosolic transport →	+0.077	+1.372	.001	.003	3	14
URINARY_TRACT	Centrosome cycle →	+0.058	+1.026	.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,275 associations by consensus.

Regulation of cilium assembly by TRIM3 expression — LIVER

Explore this box plot interactively →