Across TCGA patient cohorts, TRIM27 protein abundance is significantly associated with the RNA expression of many other genes, with 10,693 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM27-associated genes across cancer lineages are LEMD2, EHMT2, and KIF20A. Each is linked with TRIM27 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRIM27-to-partner and partner-to-TRIM27 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM27→partner) and Y-score (partner→TRIM27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LEMD2 →	+0.514	+0.250	.007	<.001	3	5
GBM	EHMT2 →	+0.579	+0.368	<.001	<.001	3	5
GBM	KIF20A →	+1.088	+0.364	<.001	<.001	3	5
GBM	CDCA7L →	+1.096	+0.356	<.001	<.001	3	5
HNSC	TUBB →	+0.796	+0.271	.002	.005	3	5
UCEC	ABCF1 →	+0.538	+0.186	.009	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,693 associations by consensus.

Exploration

TRIM27 survival (RNA) · tumor vs normal (RNA) · all TRIM27 data types