TRIM26BP

Across TCGA pan-cancer cohorts, TRIM26BP RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TRIM26BP’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where TRIM26BP RNA is repressed in tumor relative to normal tissue. In most cancer types TRIM26BP is over-expressed in tumor, although a few such as UCEC and READ show the opposite, repressed pattern.

UCEC, COAD, and READ are the cancer types where TRIM26BP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRIM26BP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	−0.240	.001	4	view →
COAD	Female	IV	+0.240	.001	1	view →
READ	All	All	−0.107	.020	1	view →
THCA	Female	All	−0.065	.042	1	view →
LIHC	All	II,III,IV	+0.026	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

TRIM26BP–UCEC

Open the UCEC breakdown →