TRIM26

Across TCGA pan-cancer cohorts, TRIM26 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TRIM26 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TRIM26 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TRIM26 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where TRIM26 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	1.000	0.207	.002	23	view →
PDAC	DFS	Median	II,III,IV	0.924	0.603	.001	18	view →
LSCC	DFS	Quartile	II,III,IV	0.450	0.873	.005	9	view →
CCRCC	DFS	Tertile	IV	0.108	0.861	.024	6	view →
HNSC	DFS	Median	III,IV	1.000	0.937	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TRIM26–LUAD (OS)

Open the LUAD breakdown →