TRIM26

Across TCGA cell cohorts, TRIM26 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,039 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM26-associated GO terms across cancer lineages are Endosomal vesicle fusion, DNA replication-dependent chromatin assembly, and Vacuolar transport. Each is linked with TRIM26 in more than 11 cancer types. Because this analysis shows association rather than direction, both TRIM26-to-partner and partner-to-TRIM26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal vesicle fusion grouped by TRIM26-low versus TRIM26-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM26→partner) and Y-score (partner→TRIM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Endosomal vesicle fusion →	+0.104	+0.797	.002	<.001	2	12
BREAST	DNA replication-dependent chromatin assembly →	+0.136	+0.912	<.001	.001	3	11
LUNG_SCLC	Vacuolar transport →	+0.082	+0.689	<.001	<.001	3	11
BLOOD_Leukemia	Positive regulation of DNA-templated DNA replication →	+0.085	+0.694	<.001	.001	3	11
BREAST	Negative regulation of cell cycle process →	+0.049	+0.846	.006	.002	3	10
CNS	Positive regulation of mitotic cytokinesis →	+0.097	+0.440	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,039 associations by consensus.

Endosomal vesicle fusion by TRIM26 expression — STOMACH

Explore this box plot interactively →