TRIM24

Across TCGA patient cohorts, TRIM24 protein abundance is significantly associated with the RNA expression of many other genes, with 20,767 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM24-associated genes across cancer lineages are PAXIP1, LMBR1, and ACTR3B. Each is linked with TRIM24 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRIM24-to-partner and partner-to-TRIM24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM24 versus PAXIP1 in LSCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM24→partner) and Y-score (partner→TRIM24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PAXIP1 →	+0.584	+0.294	<.001	<.001	3	10
HNSC	LMBR1 →	+0.627	+0.317	<.001	<.001	3	8
BRCA	ACTR3B →	+0.617	+0.255	<.001	<.001	3	8
LSCC	CBLL1 →	+0.486	+0.313	<.001	<.001	3	7
LSCC	RBM28 →	+0.485	+0.362	<.001	<.001	3	7
UCEC	ZNF212 →	+0.662	+0.238	.002	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,767 associations by consensus.

TRIM24 vs PAXIP1 — LSCC

Explore this scatter interactively →