TRIM24

Across TCGA cell cohorts, TRIM24 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,771 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TRIM24-associated GO terms across cancer lineages are Regulation of nucleobase-containing compound transport, Regulation of DNA repair, and Regulation of nucleotide-excision repair. Each is linked with TRIM24 in more than 12 cancer types. Because this analysis shows association rather than direction, both TRIM24-to-partner and partner-to-TRIM24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleobase-containing compound transport grouped by TRIM24-low versus TRIM24-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM24→partner) and Y-score (partner→TRIM24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of nucleobase-containing compound transport →	+0.115	+0.973	<.001	<.001	3	13
SOFT_TISSUE	Regulation of DNA repair →	+0.079	+1.215	<.001	<.001	3	13
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.110	+0.844	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA repair →	+0.074	+0.980	<.001	.003	3	12
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.066	+1.099	.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair →	+0.084	+0.956	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,771 associations by consensus.

Regulation of nucleobase-containing compound transport by TRIM24 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →