TRIM23

Across TCGA patient cohorts, TRIM23 protein abundance is significantly associated with the RNA expression of many other genes, with 564 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM23-associated genes across cancer lineages are PPM1A, PSMD10, and DCTN6. Each is linked with TRIM23 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM23-to-partner and partner-to-TRIM23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM23 versus PPM1A in GBM, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM23→partner) and Y-score (partner→TRIM23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPM1A →	-0.588	-0.757	<.001	.001	3	1
GBM	PSMD10 →	-0.318	-0.655	.004	.003	3	1
GBM	DCTN6 →	-0.482	-0.740	.001	.005	3	1
GBM	SNAPC2 →	+0.358	+0.606	<.001	.001	3	1
GBM	SYDE1 →	+0.649	+0.799	<.001	.001	3	1
GBM	KXD1 →	+0.320	+0.758	.008	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 564 associations by consensus.

TRIM23 vs PPM1A — GBM

Explore this scatter interactively →