TRIM22

Across TCGA patient cohorts, TRIM22 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,036 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRIM22-associated proteins across cancer lineages are UBA7, FNBP1, and IFIT1. Each is linked with TRIM22 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRIM22-to-partner and partner-to-TRIM22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM22 versus UBA7 in LSCC, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM22→partner) and Y-score (partner→TRIM22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBA7 →	+0.495	+1.047	<.001	<.001	3	10
HNSC	FNBP1 →	+0.393	+0.911	<.001	<.001	3	10
HNSC	IFIT1 →	+1.117	+1.120	<.001	<.001	3	10
UCEC	PSMB10 →	+0.705	+1.276	<.001	<.001	3	10
LSCC	PSMB6 →	-0.522	-0.955	<.001	<.001	3	10
HNSC	LAP3 →	+0.660	+1.183	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,036 associations by consensus.

TRIM22 vs UBA7 — LSCC

Explore this scatter interactively →