TRIM22

Across TCGA patient cohorts, TRIM22 protein abundance is significantly associated with the RNA expression of many other genes, with 13,848 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRIM22-associated genes across cancer lineages are ETV7, SLC15A3, and OAS2. Each is linked with TRIM22 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRIM22-to-partner and partner-to-TRIM22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM22 versus ETV7 in BRCA, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM22→partner) and Y-score (partner→TRIM22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ETV7 →	+1.497	+0.596	<.001	<.001	3	10
HNSC	SLC15A3 →	+0.884	+0.614	<.001	<.001	3	10
UCEC	OAS2 →	+1.230	+0.637	<.001	<.001	3	10
OV	BTN3A3 →	+1.152	+0.570	<.001	.001	3	10
GBM	IFIH1 →	+1.121	+0.575	<.001	<.001	3	10
HNSC	TRIM21 →	+1.368	+0.781	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,848 associations by consensus.

TRIM22 vs ETV7 — BRCA

Explore this scatter interactively →