TRIM21

Across TCGA cell cohorts, TRIM21 RNA expression is significantly associated with the RNA expression of many other genes, with 10,127 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRIM21-associated genes across cancer lineages are ILK, TRIM5, and RHOG. Each is linked with TRIM21 in more than 18 cancer types. Because this analysis shows association rather than direction, both TRIM21-to-partner and partner-to-TRIM21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM21 versus ILK in LUNG_SCLC, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM21→partner) and Y-score (partner→TRIM21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	ILK →	+1.304	+1.805	<.001	<.001	3	19
STOMACH	TRIM5 →	+1.941	+1.918	<.001	<.001	3	17
BONE	RHOG →	+1.334	+2.098	<.001	<.001	3	17
URINARY_TRACT	RNH1 →	+1.089	+1.096	<.001	<.001	3	16
BREAST	DDX60 →	+2.384	+1.443	<.001	<.001	3	16
LUNG_SCLC	TRIM68 →	+2.073	+1.703	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,127 associations by consensus.

TRIM21 vs ILK — LUNG_SCLC

Explore this scatter interactively →