TRIM2

Across TCGA patient cohorts, TRIM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,222 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM2-associated proteins across cancer lineages are TRIM2_S428, TRIM2_T371, and TRIM2_S440. Each is linked with TRIM2 in more than 8 cancer types. Because this analysis shows association rather than direction, both TRIM2-to-partner and partner-to-TRIM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM2 versus TRIM2_S428 in HNSC, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM2→partner) and Y-score (partner→TRIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRIM2_S428 →	+2.020	+1.841	<.001	<.001	3	9
HNSC	TRIM2_T371 →	+1.059	+1.404	<.001	<.001	3	9
LUAD	TRIM2_S440 →	+1.465	+0.998	<.001	<.001	3	6
LUAD	MAP2_S833 →	+1.083	+0.822	<.001	<.001	3	6
UCEC	DDAH1 →	+0.626	+0.962	<.001	<.001	3	6
GBM	VSIR →	-0.512	-0.531	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,222 associations by consensus.

TRIM2 vs TRIM2_S428 — HNSC

Explore this scatter interactively →