TRIM2

Across TCGA cell cohorts, TRIM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,897 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM2-associated GO terms across cancer lineages are Positive regulation of lymphocyte differentiation, Regulation of T cell differentiation, and Positive regulation of T cell differentiation. Each is linked with TRIM2 in more than 10 cancer types. Because this analysis shows association rather than direction, both TRIM2-to-partner and partner-to-TRIM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of lymphocyte differentiation grouped by TRIM2-low versus TRIM2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM2→partner) and Y-score (partner→TRIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of lymphocyte differentiation →	+0.076	+0.983	.002	.005	3	11
OVARY	Regulation of T cell differentiation →	+0.072	+1.494	<.001	<.001	3	10
URINARY_TRACT	Positive regulation of T cell differentiation →	+0.108	+1.302	<.001	.002	3	10
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.100	+1.754	<.001	.001	3	10
BONE	Vesicle budding from membrane →	+0.065	+1.247	<.001	.004	3	10
PANCREAS	Regulation of T cell mediated immune response to tumor cell →	+0.109	+1.460	.007	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,897 associations by consensus.

Positive regulation of lymphocyte differentiation by TRIM2 expression — URINARY_TRACT

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