TRIM17

Across TCGA cell cohorts, TRIM17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,297 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM17-associated GO terms across cancer lineages are Stress granule assembly, Regulation of RNA splicing, and Regulation of mRNA processing. Each is linked with TRIM17 in more than 14 cancer types. Because this analysis shows association rather than direction, both TRIM17-to-partner and partner-to-TRIM17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Stress granule assembly grouped by TRIM17-low versus TRIM17-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM17→partner) and Y-score (partner→TRIM17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Stress granule assembly →	+0.119	+0.579	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.077	+0.886	<.001	.007	3	15
BREAST	Regulation of mRNA processing →	+0.074	+1.379	<.001	<.001	3	15
URINARY_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.109	+1.098	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.135	+1.090	<.001	.001	2	15
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.122	+0.528	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,297 associations by consensus.

Stress granule assembly by TRIM17 expression — LARGE_INTESTINE

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