Across TCGA cell cohorts, TRIM16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,201 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TRIM16-associated GO terms across cancer lineages are Positive regulation of retinoic acid receptor signaling pathway, Cell-substrate junction organization, and Cell-substrate junction assembly. Each is linked with TRIM16 in more than 11 cancer types. Because this analysis shows association rather than direction, both TRIM16-to-partner and partner-to-TRIM16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM16→partner) and Y-score (partner→TRIM16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of retinoic acid receptor signaling pathway →	+0.206	+1.462	<.001	<.001	3	12
URINARY_TRACT	Cell-substrate junction organization →	+0.162	+1.852	<.001	<.001	3	12
URINARY_TRACT	Cell-substrate junction assembly →	+0.163	+1.754	.001	<.001	3	12
BONE	Schwann cell differentiation →	+0.115	+1.528	.006	.002	3	11
LARGE_INTESTINE	Membrane raft assembly →	+0.170	+0.875	.002	.006	3	11
STOMACH	Type II interferon-mediated signaling pathway →	+0.179	+1.270	.002	.008	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,201 associations by consensus.

Exploration

TRIM16 survival (RNA) · tumor vs normal (RNA) · all TRIM16 data types