Across TCGA patient cohorts, TRIM15 protein abundance is significantly associated with the RNA expression of many other genes, with 925 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRIM15-associated genes across cancer lineages are ACSF2, SMPDL3A, and ELOCP28. Each is linked with TRIM15 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM15-to-partner and partner-to-TRIM15 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM15→partner) and Y-score (partner→TRIM15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ACSF2 →	-1.330	-0.571	.002	.003	3	2
PDAC	SMPDL3A →	+0.821	+0.911	.002	.005	3	2
COAD	ELOCP28 →	-0.166	-0.408	.002	.001	3	1
COAD	RSPH10B →	-0.041	-0.395	.004	.007	3	1
COAD	MAP3K7CL →	-0.396	-0.370	.003	<.001	3	1
COAD	SYNPR →	+0.524	+0.416	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 925 associations by consensus.

Exploration

TRIM15 survival (RNA) · tumor vs normal (RNA) · all TRIM15 data types