TRIAP1

Across TCGA patient cohorts, TRIAP1 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIAP1-associated genes across cancer lineages are MRPL57P6, RNU6-1273P, and OTOP1. Each is linked with TRIAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIAP1-to-partner and partner-to-TRIAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPL57P6 grouped by TRIAP1-low versus TRIAP1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIAP1→partner) and Y-score (partner→TRIAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MRPL57P6 →	+0.199	+7.930	<.001	.008	3	2
BLCA	RNU6-1273P →	+0.373	+7.640	<.001	.009	3	2
UCEC	OTOP1 →	+0.474	+3.076	.002	.005	3	1
UCEC	SNORD116-4 →	+1.676	+3.355	<.001	.008	3	1
LUAD	RNA5SP204 →	+0.789	+7.930	<.001	.008	3	1
LUAD	MIR515-2 →	+0.371	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

MRPL57P6 by TRIAP1 expression — LUAD

Explore this box plot interactively →