Across TCGA pan-cancer cohorts, TRGV9 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TRGV9 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TRGV9 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRGV9 expression acts as an unfavorable survival marker.

LUAD and UCEC are the cancer types where TRGV9 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.229	0.813	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TRGV9 tumor-vs-normal RNA expression · all TRGV9 data types