Across TCGA patient cohorts, TRGV9 mutation is significantly associated with the RNA expression of many other genes, with 110 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRGV9-associated genes across cancer lineages are MIR6784, SNRNP25, and PMPCA. Each is linked with TRGV9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRGV9-to-partner and partner-to-TRGV9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGV9→partner) and Y-score (partner→TRGV9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6784 →	+0.860	+2.723	.005	.009	3	1
UCEC	SNRNP25 →	+0.538	+3.397	.006	.004	3	1
UCEC	PMPCA →	+0.629	+3.354	<.001	.005	3	1
UCEC	URM1 →	+0.571	+3.354	<.001	.005	3	1
UCEC	LETM1 →	+0.560	+3.364	.003	.005	3	1
UCEC	THOP1 →	+0.572	+3.332	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 110 associations by consensus.

Exploration

TRGV9 survival (RNA) · tumor vs normal (RNA) · all TRGV9 data types