Across TCGA patient cohorts, TRGV6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,219 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRGV6-associated proteins across cancer lineages are DOCK2, LPXN, and ARHGAP25. Each is linked with TRGV6 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRGV6-to-partner and partner-to-TRGV6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGV6→partner) and Y-score (partner→TRGV6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DOCK2 →	+0.475	+0.457	<.001	<.001	3	7
UCEC	LPXN →	+0.555	+0.627	<.001	<.001	3	7
LSCC	ARHGAP25 →	+0.485	+0.452	<.001	<.001	3	7
HNSC	RCSD1 →	+0.491	+0.910	<.001	<.001	3	6
HNSC	SAMSN1 →	+0.502	+0.718	<.001	<.001	3	6
UCEC	WAS →	+0.523	+0.613	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,219 associations by consensus.

Exploration

TRGV6 survival (RNA) · tumor vs normal (RNA) · all TRGV6 data types