Across TCGA patient cohorts, TRGV5 mutation is significantly associated with the RNA expression of many other genes, with 95 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRGV5-associated genes across cancer lineages are ATF4P2, YWHAZP8, and IGHD3-16. Each is linked with TRGV5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRGV5-to-partner and partner-to-TRGV5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGV5→partner) and Y-score (partner→TRGV5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATF4P2 →	+0.070	+3.599	<.001	.001	3	2
LUAD	YWHAZP8 →	+0.064	+4.343	<.001	.001	3	2
UCEC	IGHD3-16 →	+1.432	+2.832	.001	.007	3	2
UCEC	COX6CP12 →	+0.123	+3.997	<.001	.009	3	2
UCEC	LINC01050 →	+0.270	+3.064	.002	.005	3	1
UCEC	MIR4727 →	+0.603	+3.814	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 95 associations by consensus.

Exploration

TRGV5 survival (RNA) · tumor vs normal (RNA) · all TRGV5 data types