Across TCGA patient cohorts, TRGV3 mutation is significantly associated with the RNA expression of many other genes, with 690 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRGV3-associated genes across cancer lineages are RNU6-718P, RN7SL362P, and MIR3973. Each is linked with TRGV3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRGV3-to-partner and partner-to-TRGV3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGV3→partner) and Y-score (partner→TRGV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-718P →	+0.557	+4.906	<.001	.003	3	3
HNSC	RN7SL362P →	+0.262	+5.600	<.001	<.001	3	2
HNSC	MIR3973 →	+0.321	+5.763	<.001	.001	3	2
SKCM	MTND1P33 →	+0.028	+4.302	<.001	.007	3	2
SKCM	TRMT10BP1 →	+0.066	+4.512	<.001	<.001	3	2
SKCM	LINC01243 →	+0.083	+3.071	.007	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 690 associations by consensus.

Exploration

TRGV3 survival (RNA) · tumor vs normal (RNA) · all TRGV3 data types