Across TCGA patient cohorts, TRGV3 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRGV3-associated genes across cancer lineages are Tuberin_pT1462, JNK2, and Ku80. Each is linked with TRGV3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRGV3-to-partner and partner-to-TRGV3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGV3→partner) and Y-score (partner→TRGV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Tuberin_pT1462 →	+0.445	+2.817	.001	.036	3	1
UCEC	JNK2 →	+0.385	+2.817	.001	.036	2	1
UCEC	Ku80 →	+0.399	+2.820	.005	.036	1	1
UCEC	VEGFR2 →	+0.441	+2.820	.015	.036	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

TRGV3 survival (RNA) · tumor vs normal (RNA) · all TRGV3 data types