TRGC2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRGC2 mutation is significantly associated with the RNA expression of many other genes, with 1,291 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRGC2-associated genes across cancer lineages are UBC, C12orf43, and CHAF1A. Each is linked with TRGC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRGC2-to-partner and partner-to-TRGC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGC2→partner) and Y-score (partner→TRGC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECUBC →+0.390+3.628.004.00132
UCECC12orf43 →+0.267+3.658.009.00132
UCECCHAF1A →+0.612+4.269.001<.00132
UCECSMIM4 →+0.523+2.545<.001.00132
UCECSTIP1 →+0.586+3.609<.001.00132
UCECZNF778 →+0.552+3.756<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,291 associations by consensus.

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