Across TCGA patient cohorts, TRGC1 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRGC1-associated genes across cancer lineages are JNK2, TFRC, and C-Raf. Each is linked with TRGC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRGC1-to-partner and partner-to-TRGC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGC1→partner) and Y-score (partner→TRGC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.289	+3.196	.002	.009	3	1
UCEC	TFRC →	+0.525	+2.999	.040	.035	3	1
UCEC	C-Raf →	+0.158	+2.459	.022	.020	3	1
UCEC	Rab11 →	-0.140	-2.980	.046	.036	2	1
UCEC	FoxM1 →	+0.279	+3.584	.025	.002	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

TRGC1 survival (RNA) · tumor vs normal (RNA) · all TRGC1 data types