TRERNA1

Across TCGA pan-cancer cohorts, TRERNA1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TRERNA1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where TRERNA1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRERNA1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

BRCA, COAD, and THCA are the cancer types where TRERNA1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRERNA1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	+0.048	.011	6	view →
COAD	All	All	+0.082	.026	2	view →
THCA	Male	All	−0.124	.006	1	view →
KICH	Female	III,IV	−0.116	.028	1	view →
HNSC	Male	IV	−0.082	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

TRERNA1–BRCA

Open the BRCA breakdown →