TRERF1

Across TCGA cell cohorts, TRERF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,477 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRERF1-associated GO terms across cancer lineages are Regulation of metaphase plate congression, Cellular response to progesterone stimulus, and Microtubule nucleation. Each is linked with TRERF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRERF1-to-partner and partner-to-TRERF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of metaphase plate congression grouped by TRERF1-low versus TRERF1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRERF1→partner) and Y-score (partner→TRERF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of metaphase plate congression →	+0.100	+1.101	.009	.009	2	10
BLOOD_Lymphoma	Cellular response to progesterone stimulus →	+0.412	+1.216	<.001	<.001	3	9
BONE	Microtubule nucleation →	+0.129	+1.171	.004	.003	3	8
BONE	Viral translational termination-reinitiation →	+0.071	+0.987	.001	.002	3	8
STOMACH	Glucose catabolic process →	+0.108	+1.648	.007	.004	3	8
CNS	Microtubule cytoskeleton organization involved in mitosis →	+0.072	+0.687	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,477 associations by consensus.

Regulation of metaphase plate congression by TRERF1 expression — LUNG_NSCLC_LUSC

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