Across TCGA pan-cancer cohorts, TREML3P Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TREML3P data layer compared with 28 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TREML3P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TREML3P expression acts as an unfavorable survival marker, although some lineages such as MESO show a favorable association.

UCEC and MESO are the cancer types where TREML3P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
MESO	DFS	Median	All	1.000	0.179	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TREML3P tumor-vs-normal RNA expression · all TREML3P data types