TREML2

Across TCGA cell cohorts, TREML2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,578 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TREML2-associated GO terms across cancer lineages are Cellular response to steroid hormone stimulus, Cellular response to chemical stress, and Viral process. Each is linked with TREML2 in more than 7 cancer types. Because this analysis shows association rather than direction, both TREML2-to-partner and partner-to-TREML2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to steroid hormone stimulus grouped by TREML2-low versus TREML2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TREML2→partner) and Y-score (partner→TREML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cellular response to steroid hormone stimulus →	+0.072	+0.348	<.001	.006	3	8
LARGE_INTESTINE	Cellular response to chemical stress →	+0.041	+0.912	<.001	.001	3	8
PANCREAS	Viral process →	+0.066	+0.596	<.001	.007	3	7
PANCREAS	Regulation of endoplasmic reticulum unfolded protein response →	+0.081	+0.384	<.001	.002	3	7
PANCREAS	Negative regulation of endoplasmic reticulum unfolded protein response →	+0.102	+0.507	<.001	.008	3	7
PANCREAS	Regulation of response to endoplasmic reticulum stress →	+0.079	+0.564	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,578 associations by consensus.

Cellular response to steroid hormone stimulus by TREML2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →