TREML1

Across TCGA patient cohorts, TREML1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,341 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TREML1-associated genes across cancer lineages are HBA1, HBB, and PPBP. Each is linked with TREML1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TREML1-to-partner and partner-to-TREML1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TREML1 versus HBA1 in PDAC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TREML1→partner) and Y-score (partner→TREML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HBA1 →	+2.104	+0.734	.002	.001	3	3
PDAC	HBB →	+3.440	+0.701	.002	.003	3	3
UCEC	PPBP →	+1.338	+0.919	.007	.005	3	2
PDAC	RGS2 →	+1.478	+0.711	<.001	<.001	3	2
LSCC	GTF2A1 →	-0.588	-0.486	<.001	<.001	3	2
PDAC	ZFP91 →	-0.506	-0.810	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,341 associations by consensus.

TREML1 vs HBA1 — PDAC

Explore this scatter interactively →