TREHP1

Across TCGA pan-cancer cohorts, TREHP1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of TREHP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where TREHP1 RNA is repressed in tumor relative to normal tissue. In most cancer types TREHP1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and KIRC are the cancer types where TREHP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TREHP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−1.184	<.001	9	view →
LUSC	All	III,IV	−1.111	<.001	9	view →
KIRC	All	III,IV	−0.361	<.001	9	view →
THCA	All	All	−0.432	.001	5	view →
READ	All	III,IV	−0.580	.010	2	view →
BRCA	Female	II,III,IV	−0.233	.017	2	view →
KICH	All	IV	−0.914	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

TREHP1–LUAD

Open the LUAD breakdown →