TREH

Across TCGA patient cohorts, TREH RNA expression is significantly associated with the protein abundance of many other proteins, with 14,131 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TREH-associated proteins across cancer lineages are PHLDB1_S443, TNS1_S1400, and MAP1A_S1776. Each is linked with TREH in more than 6 cancer types. Because this analysis shows association rather than direction, both TREH-to-partner and partner-to-TREH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TREH versus PHLDB1_S443 in LSCC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TREH→partner) and Y-score (partner→TREH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PHLDB1_S443 →	+0.482	+0.421	<.001	.002	3	7
PDAC	TNS1_S1400 →	+0.886	+0.702	<.001	<.001	3	6
UCEC	MAP1A_S1776 →	+0.619	+0.615	.005	<.001	3	6
BRCA	PHLDB1 →	+0.445	+0.382	<.001	<.001	3	6
HNSC	PHLDB1_S404 →	+0.632	+0.554	<.001	<.001	3	6
PDAC	RPL5 →	-0.226	-0.700	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,131 associations by consensus.

TREH vs PHLDB1_S443 — LSCC

Explore this scatter interactively →