TREH

Across TCGA cell cohorts, TREH RNA expression is significantly associated with the go_rna of many other GO terms, with 1,539 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TREH-associated GO terms across cancer lineages are Disaccharide catabolic process, Actomyosin contractile ring organization, and Retinoic acid receptor signaling pathway. Each is linked with TREH in more than 5 cancer types. Because this analysis shows association rather than direction, both TREH-to-partner and partner-to-TREH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Disaccharide catabolic process grouped by TREH-low versus TREH-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TREH→partner) and Y-score (partner→TREH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Disaccharide catabolic process →	+0.226	+0.511	<.001	.006	3	6
STOMACH	Actomyosin contractile ring organization →	+0.135	+0.612	<.001	.004	3	5
LARGE_INTESTINE	Retinoic acid receptor signaling pathway →	+0.070	+0.368	.003	<.001	3	4
SKIN	Cellular response to fructose stimulus →	+0.107	+0.231	<.001	<.001	3	4
CNS	Protein localization to lysosome →	+0.071	+0.122	<.001	.004	3	4
CNS	Kynurenine metabolic process →	-0.389	-0.143	.004	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,539 associations by consensus.

Disaccharide catabolic process by TREH expression — KIDNEY

Explore this box plot interactively →