TRDV3

Across TCGA patient cohorts, TRDV3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,940 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TRDV3-associated GO terms across cancer lineages are Positive thymic T cell selection, Antigen receptor-mediated signaling pathway, and T cell receptor signaling pathway. Each is linked with TRDV3 in more than 23 cancer types. Because this analysis shows association rather than direction, both TRDV3-to-partner and partner-to-TRDV3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive thymic T cell selection grouped by TRDV3-low versus TRDV3-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDV3→partner) and Y-score (partner→TRDV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Positive thymic T cell selection →	+0.167	+2.361	<.001	<.001	3	24
CHOL	Antigen receptor-mediated signaling pathway →	+0.073	+0.321	<.001	<.001	2	24
STAD	T cell receptor signaling pathway →	+0.056	+0.261	<.001	<.001	3	23
ESCA	Positive regulation of B cell activation →	+0.048	+0.103	<.001	<.001	3	23
STAD	Interleukin-6 production →	+0.046	+0.306	<.001	<.001	3	22
CHOL	T-helper 1 type immune response →	+0.073	+0.185	<.001	.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,940 associations by consensus.

Positive thymic T cell selection by TRDV3 expression — THYM

Explore this box plot interactively →