TRDV3

Across TCGA patient cohorts, TRDV3 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRDV3-associated genes across cancer lineages are ABHD17AP9, MIR8082, and OR5I1. Each is linked with TRDV3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRDV3-to-partner and partner-to-TRDV3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABHD17AP9 grouped by TRDV3-low versus TRDV3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDV3→partner) and Y-score (partner→TRDV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	ABHD17AP9 →	+0.074	+7.640	<.001	.009	3	1
UCEC	MIR8082 →	+1.258	+5.146	<.001	.001	3	1
UCEC	OR5I1 →	+0.093	+5.226	<.001	.003	3	1
UCEC	OR6C72P →	+0.145	+5.027	<.001	.004	3	1
UCEC	TRAJ57 →	+1.482	+4.903	<.001	.002	3	1
UCEC	TRAJ46 →	+0.742	+5.453	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ABHD17AP9 by TRDV3 expression — BLCA

Explore this box plot interactively →