Across TCGA pan-cancer cohorts, TRDV2 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated TRDV2 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TRDV2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRDV2 expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

BRCA, HNSC, and ESCA are the cancer types where TRDV2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.658	0.533	.001	103	view →
HNSC	DFS	Tertile	All	0.793	0.674	.007	63	view →
ESCA	DFS	Tertile	II,III,IV	0.529	0.312	.026	42	view →
LIHC	DFS	Tertile	II,III,IV	0.268	0.448	.012	39	view →
ACC	OS	Tertile	II,III,IV	0.180	0.738	.003	36	view →
BLCA	DFS	Tertile	II,III,IV	0.652	0.491	.024	33	view →
LAML	DFS	Tertile	All	0.698	0.447	.002	32	view →
CESC	DFS	Quartile	All	0.854	0.700	.005	32	view →
DLBC	DFS	Median	All	0.973	0.550	.004	30	view →
SKCM	OS	Tertile	III,IV	0.508	0.349	.012	20	view →
UCEC	OS	Tertile	II,III,IV	0.990	0.834	.039	18	view →
KIRC	DFS	Quartile	IV	0.815	0.483	.026	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

Exploration

Same gene, other analysis: TRDV2 tumor-vs-normal RNA expression · all TRDV2 data types