Across TCGA patient cohorts, TRDN RNA expression is significantly associated with the protein abundance of many other proteins, with 9,220 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TRDN-associated proteins across cancer lineages are PLIN4, ITSN1, and MAP1B_S541. Each is linked with TRDN in more than 4 cancer types. Because this analysis shows association rather than direction, both TRDN-to-partner and partner-to-TRDN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDN→partner) and Y-score (partner→TRDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PLIN4 →	+1.360	+0.066	<.001	<.001	3	5
PDAC	ITSN1 →	+0.305	+0.038	<.001	.002	3	4
LSCC	MAP1B_S541 →	+0.957	+0.422	<.001	.008	3	3
LSCC	MAP1LC3A →	+0.652	+0.569	.001	.003	3	3
HNSC	NEXN →	+0.897	+2.140	<.001	<.001	3	3
BRCA	NID1 →	+0.590	+0.306	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,220 associations by consensus.

Exploration

TRDN survival (RNA) · tumor vs normal (RNA) · all TRDN data types