TRDN

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TRDN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,019 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRDN-associated GO terms across cancer lineages are Axoneme assembly, Renal system process, and NADH dehydrogenase complex assembly. Each is linked with TRDN in more than 4 cancer types. Because this analysis shows association rather than direction, both TRDN-to-partner and partner-to-TRDN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDN→partner) and Y-score (partner→TRDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaAxoneme assembly →-0.032-0.372<.001.00135
BONERenal system process →-0.143-0.770<.001.00635
LUNG_NSCLC_LUADNADH dehydrogenase complex assembly →+0.051+0.212<.001.00734
LUNG_NSCLC_LUADMitochondrial respiratory chain complex I assembly →+0.051+0.212<.001.00734
CNSCellular component assembly involved in morphogenesis →-0.046-0.380<.001.00434
CNSProtein-RNA complex assembly →+0.029+0.266.005.00334
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,019 associations by consensus.

Exploration