TRDMT1

Across TCGA patient cohorts, TRDMT1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,506 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRDMT1-associated genes across cancer lineages are GLA, G6PD, and NQO1. Each is linked with TRDMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRDMT1-to-partner and partner-to-TRDMT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRDMT1 versus GLA in BRCA, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDMT1→partner) and Y-score (partner→TRDMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GLA →	-0.595	-0.394	.004	.007	3	2
LSCC	G6PD →	-0.844	-0.301	<.001	<.001	3	2
LSCC	NQO1 →	-1.408	-0.384	<.001	<.001	3	2
PDAC	TSPAN10 →	-0.507	-0.455	.005	.003	3	2
GBM	H2BU1 →	-1.549	-0.346	.002	.004	3	2
LUAD	CHODL-AS1 →	+1.059	+0.254	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,506 associations by consensus.

TRDMT1 vs GLA — BRCA

Explore this scatter interactively →