TRDMT1

Across TCGA cell cohorts, TRDMT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,023 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRDMT1-associated GO terms across cancer lineages are Mitotic spindle organization, Protein localization to chromosome, and Positive regulation of chromosome segregation. Each is linked with TRDMT1 in more than 14 cancer types. Because this analysis shows association rather than direction, both TRDMT1-to-partner and partner-to-TRDMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle organization grouped by TRDMT1-low versus TRDMT1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDMT1→partner) and Y-score (partner→TRDMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Mitotic spindle organization →	+0.074	+0.452	<.001	.005	3	15
LARGE_INTESTINE	Protein localization to chromosome →	+0.076	+0.662	<.001	<.001	3	14
BREAST	Positive regulation of chromosome segregation →	+0.133	+0.826	.001	.001	3	14
PANCREAS	Microtubule cytoskeleton organization involved in mitosis →	+0.075	+0.654	<.001	.001	3	14
BLOOD_Myeloma	Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.124	+1.005	.002	.002	3	13
KIDNEY	Spindle assembly →	+0.053	+0.747	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,023 associations by consensus.

Mitotic spindle organization by TRDMT1 expression — SKIN

Explore this box plot interactively →