TRDD3

Across TCGA patient cohorts, TRDD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 3,145 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TRDD3-associated proteins across cancer lineages are PLCG1_S1263, CGN_S155, and ALDH18A1. Each is linked with TRDD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRDD3-to-partner and partner-to-TRDD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRDD3 versus PLCG1_S1263 in HNSC, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDD3→partner) and Y-score (partner→TRDD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PLCG1_S1263 →	+0.301	+0.825	.009	.008	3	2
BRCA	CGN_S155 →	-0.835	-0.510	.006	.002	3	2
HNSC	ALDH18A1 →	-0.277	-0.925	<.001	.001	3	2
BRCA	SHROOM3_S677 →	-0.796	-0.554	.003	.002	3	2
UCEC	VWA2 →	+0.741	+2.155	.001	<.001	3	2
CCRCC	ABCF3_S115 →	-1.226	-1.405	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,145 associations by consensus.

TRDD3 vs PLCG1_S1263 — HNSC

Explore this scatter interactively →