TRDD2

Across TCGA patient cohorts, TRDD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,618 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRDD2-associated GO terms across cancer lineages are Intermembrane lipid transfer, Negative regulation of leukocyte apoptotic process, and Adaptive thermogenesis. Each is linked with TRDD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRDD2-to-partner and partner-to-TRDD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intermembrane lipid transfer grouped by TRDD2-low versus TRDD2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDD2→partner) and Y-score (partner→TRDD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Intermembrane lipid transfer →	+0.098	+0.253	<.001	.001	3	5
STAD	Negative regulation of leukocyte apoptotic process →	+0.183	+0.536	<.001	<.001	3	5
STAD	Adaptive thermogenesis →	+0.125	+0.396	<.001	<.001	3	5
STAD	Regulation of calcium ion transport →	+0.090	+0.521	<.001	<.001	3	5
STAD	Regulation of pattern recognition receptor signaling pathway →	+0.156	+0.510	<.001	<.001	3	5
STAD	Lymphocyte apoptotic process →	+0.188	+0.270	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,618 associations by consensus.

Intermembrane lipid transfer by TRDD2 expression — STAD

Explore this box plot interactively →